Metastatic Tumor

Lymphangitic carcinoma, lymph node metastasis

The accentuated linear markings (arrow) in this slice of lung represent tumor in lymphatics, which follow bronchovascular bundles and interlobular septa. Whitish tumor deposits are also present in the black hilar lymph nodes.

Lymphangitic carcinoma

A low-power view shows the widening of the lymphatics by tumor. The pleura is at the top.

Lymphangitic carcinoma

Here, perivenous lymphatics are filled with gland-forming, metastatic adenocarcinoma.

Metastatic tumor nodule

Hematogenously disseminated tumor may gain access to the lung parenchyma by enzymes that destroy basement membranes and extracellular matrix.

Here, an extravascular tumor nodule is present at the lower right.