Tumor cells have abundant cytoplasm, clumped chromatin (blue), and pink nucleoli (arrow), but no evidence of gland formation, mucin production, bridges, or pearls. A giant cell variant occurs.
Tumors
Large cell carcinoma
|
|
Tumor cells have abundant cytoplasm, clumped chromatin (blue), and pink nucleoli (arrow), but no evidence of gland formation, mucin production, bridges, or pearls. A giant cell variant occurs. | ||||||
Adenocarcinoma
|
|
Adenocarcinomas show gland formation or neutral mucin production (PAS-D+). This tumor is composed of glands. The stroma has many inflammatory cells. | ||||||
Bronchioloalveolar carcinoma
|
|
Columnar tumor cells line preformed alveolar walls and stimulate some production of fibrous tissue in the walls; solitary nodular types outnumber the multifocal diffuse types. | ||||||
|
|
Contrast the enlarged, columnar tumor cells (lower right) with the normal, ciliated epithelium (upper left). | ||||||
