UIP is characterized by patchy architectural distortion (honeycombing at lower left). This view also shows fibrosis radiating from bronchovascular bundles (B), interlobular septa (S), and the pleura (left).
Interstitial Pneumonias
Usual interstitial pneumonia (UIP)
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UIP is characterized by patchy architectural distortion (honeycombing at lower left). This view also shows fibrosis radiating from bronchovascular bundles (B), interlobular septa (S), and the pleura (left). | ||||||
Must have Honeycombing, Old fibrosis, Recent granulation tissue, and Normal lung (HORN).
Usual interstitial pneumonia
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Black arrow--Normal lung Green arrow--Alveolitis: alveolar wall thickening, interstitial inflammation, type II cell hyperplasia Brown arrow--Confluent alveolitis Blue arrow--Fibrosis | ||||||
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The cellular, bluish, granulaton tissue here contrasts with the dense, pink fibrous tissue at the lower left. Together they indicate temporal heterogeneity. | ||||||
Emphysema versus honeycombing
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Left: Emphysematous spaces with thin walls Right: Honeycombed spaces with thick walls adjacent to normal lung (arrow) | ||||||
See also Case 27
