Histologic Changes
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These small arteries, 150 µm in diameter, are both abnormal. That on the right has intimal and medial thickening. That on the left appears to have a recanalized thrombus with multiple channels. An elastic tissue stain showed that the elastic laminas were absent indicating that this is a plexiform lesion. | ||||||
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A similar vessel, 160 µm in diameter, stained with the elastic-van Gieson stain shows a single elastic layer around a plexiform lesion that resembles a recanalized thrombus (large arrow). Another part of the vessel that is thrombosed has two elastic layers (paired small arrows). | ||||||
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On the other hand, this vessel (490 µm diameter) (from another case) is a thrombotic lesion with intact elastic laminas and a recanalized thrombus in the lumen. This thrombotic lesion can be distinguished from a thromboembolus only by the clinical context. | ||||||