Histologic Changes
The alveolar parenchyma shows enlarged air spaces
with walls that are widened by edematous connective tissue. Cuboid to
flat alveolar lining cells are more prominent than normal.
Small, centrally-placed, blood-filled veins
are present, but capillaries, which make contact with the
alveolar lining cells, are markedly decreased. Thick-walled
arterioles (arrows) accompany the thin-walled venous
channels.