Histologic Changes
This low-power view of the wall of the resected lung nodule shows an epithelial-lined cyst, which is surrounded by connective tissue (arrows indicate the junction with adjacent lung, which is unremarkable).
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The epithelial lining is the same as that seen in the lymph node. It has been shown in some cases that the spindled cells of the "stroma" are keratin-positive suggesting that they are epithelial elements of the yolk sac tumor and not reactive stroma [1]. | ||||||
Reference
1. Ulbright T, Roth L. A pathologic analysis of lesions following modern chemotherapy for metastatic germ-cell tumors. Pathol Annu 1990; 25 (Pt 1):313-340.
Clinical summary
Image 6