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Figure 1. Small GC Here, a small GC is composed mostly of follicular dendritic cells, which are being compressed by the central hyaline. Outline the GC. | ||||||||||
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Figure 2. "Lollipop" Pattern A typical follicle in CD-HV has a small GC and concentrically-arranged lymphocytes in the mantle zone. It is surrounded by a highly-vascular interfollicular region. The hyalinized areas represent perivascular regions. One hyalinized vessel penetrating the mantle zone, together with the associated GC, resembles a "lollipop." Find the "lollipop." | ||||||||||
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Figure 3. Rare Hyperplastic GC Not all GCs in CD-HV are small. This medium-sized one with a mixture of large dendritic cells and lymphocytes, as well as macrophages with bits of phagocytosed nuclear debris (tingible bodies), resembles a reactive GC. Note again the concentric layers of lymphocytes, typical of CD-HV, in the mantle zone. | ||||||||||
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Germinal center with compressed cells, mostly dendritic type