Occasionally, MTb infection may manifest as a solitary pulmonary nodule, or tuberculoma (figure 1A). Tuberculomas may result from either primary or postprimary MTb infection. Tuberculomas appear as rounded nodules, often circumscribed, but occasionally with a spiculated margin. They are usually located in the upper lobes. Small satellite nodules are often present, as well. These lesions often do not show enhancement following CT performed with intravenous contrast administration, although peripheral enhancement may occur. Calcification may develop over time.


Figure 1A. Tuberculoma

Frontal chest radiograph of MTb infection with tuberculoma formation shows a left apical nodule. The patient is a 55-year-old woman with squamous carcinoma of the larynx.

Find the tuberculoma.




Figure 1B. Axial CT During a Nodule Enhancement Protocol Examination

Note the left upper lobe nodule. The lack of enhancement in this study suggests that the nodule is likely benign.

Figure 1C. Axial CT Image During Transthoracic Biopsy

MTb grew in culture obtained from this procedure.

Figure 1D. Posttreatment Radiograph

Frontal chest radiograph during MTb treatment shows regression of the nodule.

See Bronchial Stenosis, AIDS

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