Figure 1. Spontaneous Pneumothorax in PCP

Frontal chest radiograph shows diffuse, bilateral, air-space opacity and bilateral pneumothoraces.


Figure 2. Histology of Talc Pleurodesis

Pleurodesis is sometimes required for recurrent pneumothorax. Here, a section of lung shows a thickened, edematous pleura with an inflammatory response to instilled talc. Note the persistence of the foamy exudate of pneumocystis in the lung.

Find an alveolus with foamy exudate.

Figure 3. Polarized Light

Viewed with polarized light, the section in Figure 2 shows talc crystals in the outer, inflamed portion of the pleura.


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Subpleural alveolus with foamy exudate of pneumocystis