Histologic Changes in the Biopsy

In the photo, the central bronchiole has an edematous wall that is infiltrated with lymphoid cells, another aspect of this interstitial pneumonia. The epithelium is partially eroded inferiorly, and the lumen contains an exudate of macrophages and some PMNs. The accompanying pulmonary artery (upper left) shows some intimal thickening (compare wall thickness in lower portion to the upward branch) that may be related to the inflammation. Alveolar walls show slight to moderate thickening, and granulation tissue or exudate fills alveoli. The overall architecture is preserved.

Clinical summaryImage 3

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