Contrasting Features of Carcinoid Tumors and Well-Differentiated Neuroendocrine Carcinomas/Atypical Carcinoid Tumor

Compare this photo of a carcinoid tumor with that of a WDNC below. Arrows mark mitoses.

Histologic Criteria for Carcinoid Tumors

Histologic Criteria for WDNC/Atypical Carcinoid [1]


1. El-Naggar A, Ballance W, Abdul Karim F, Ordóñez N, McLemore D, Giacco G, Batsakis J. Typical and atypical bronchopulmonary carcinoids. A clinicopathologic and flow cytometric study. Am J Clin Pathol 1991; 95:828-834.

2. Flieder D, Falk R, Rush W, Fleming M, Gal A, Koss M, Travis W. Proposed modified histologic criteria for diagnosis of atypical carcinoid tumors. Lab Invest 1997; 76:164a.

3. Travis W, Rush W, Flieder D, Falk R, Fleming M, Gal A, Koss M. Survival analysis of 200 pulmonary neuroendocrine tumors with clarification of criteria for atypical carcinoid and its separation from typical carcinoid. Am J Surg Pathol 1998; 22:934-944.


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