Chronic Changes in WG

This micronodular scar surrounded by chronic inflammatory cells and a few multinucleated giant cells probably represents a healed area of basophilic necrosis.

Interstitial fibrosis of a non-specific type shown here may represent healing of capillaritis.

Reference

Mark E, Flieder D, Matsubara O. Treated Wegener's granulomatosis: distinctive pathological findings in the lungs of 20 patients and what they tell us about the natural history of the disease. Hum Pathol 1997; 28:450-458.

Clinical summary Discussion

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