Histologic changes: A low-power view shows an area of consolidation. Which description best characterizes it?

A. Acute lobar pneumonia

B. Organizing lobar pneumonia

C. Granulomatosis with multinucleated giant cells and chronic inflammation

D. Atelectasis due to improper distension of the specimen

E. Endogenous lipoid pneumonia

Answer

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Answer: C. This is granulomatosis with multinucleated giant cells and chronic inflammation.

Two multinucleated giant cells are present (center near top and near bottom).

Chronic inflammatory cells are scattered throughout parenchyma that shows some granulation tissue (center left).

No granulomas are present.

Clinical summary Image 2

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