Histologic findings: Alveolar wall necrosis (A), probably ischemic in origin, is a characteristic lesion in these patients. At the arrows, the wall is inflamed. PMNs are present in the wall and in the surrounding alveolar spaces. A few macrophages are near the center top.
At higher magnification, a fibrinous exudate is present around the necrotic alveolar wall. Despite the presence of inflammation, alveolar hemorrhage is scant. The non-necrotic walls have capillaries that are distended by sickle RBCs.
Clinical summary Image 4
Table of Contents