Demographic Data, Associated Syndromes, and Presentation
of Carcinoid Tumors of the Thymus

Reference

No. of cases

Sex

Age

Associated syndromes

Presentation

Cushing's syndrome

MEN-1

Rosai, et al [11]

16

14M:2F

21-66; ave. 46

0

0

5 asympt; 11 chest pain, dyspnea, cough

Rosai, et al [12]

3

3M

36-43

0

3

1 peptic ulcer; 1 pituitary adenoma; 1 renal stones. Thymic carcinoid asympt.

Tanaka, et al [13]

1

M

32

0

0

Asympt.

Wick, et al [14]

7

5M:2F

27-67; ave. 44

1

2

1 Cushing's; 2 chest pain; 1 fatigue; 1 night sweats; 1 neck mass; 1 asympt.

Wick, et al [15]

8

6M:2F

15-65; ave. 44

4

0

3 asympt; 4 Cushing's; 1 cough, dyspnea

Birnberg, et al [16]

2

2M

24, 46

0

2

Thymic carcinoid asympt.

Wick, et al [17]

5

5M

54-78; ave. 67

1

1

2 asympt; 2 dyspnea, chest pain, cough; 1 Cushing's

Economopoulos, et al [9]

7

6M:1F

27-70; ave. 48

0

0

3 asympt; 2 dyspnea, chest pain; 1 pericarditis; 1 unknown

Mizuno, et al [4]

1

M

60

0

0

Myasthenia gravis from associated thymoma

Takayama, et al [18]

1

F

34

0

1

Chest pain

Wang, et al [10]

8

6M:2F

32-68; ave. 52

2

0

2 Cushing's; 4 dyspnea, chest pain, cough, SVC syndrome, hoarseness; 2 asympt.

Valli, et al [19]

8

6M:2F

48-60; ave. 55

0

0

Not given

Suster, et al [8]

4

3M:1F

22-43; ave. 33

0

0

4 cough, chest pain

de Montpreville, et al [1]

14

11M:3F

35-71; ave. 53

1

1

4 asympt; 5 dyspnea ± weight loss; 5 SVC syndrome

Total

85

69M:16F (4.3:1)

48.3 ave.

9

10

MEN = multiple endocrine neoplasia syndrome. SVC = superior vena caval syndrome. Asympt. = asymptomatic

Discussion

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