Clinical, Occupational, and Pathologic Features of 272 Mesothelioma Cases in Southeast England in 1987 [1]

Category

Characteristics

Category

Characteristics

Age at death

Mean 65 y (range 39-92)

Peritoneal tumors

14 (5.1%)

Sex: Entire group

Non-exposed

M:F 12.6:1 N=272

M:F 1.35:1 N=34

Metastases

150 cases (55%)

Median survival from onset of symptoms

14 mo (0-91 mo); 4% >40 mo

Asbestosis

10/258 (3.9%) pleural

5/14 (35.7%) peritoneal

Occupational exposure

236 (86.8%) shipbuilding, construction, electrical work, etc.

Asbestos bodies in lung tissue

125 (46%) cases

Asbestos bodies in tissue with no known occupational exposure

10 patients

Pleural plaques

78 (28.7%) cases

Mean latency (first exposure to death)

41 y (range 15-67 y)

Histologic types: Epithelial

Mixed

Sarcomatous

81

84

83

Duration of exposure

19 y (range 3 mo-53 y)

Median survival time: Epithelial

Mixed

Sarcomatous

12.5 mo

11 mo

9.4 mo

Ratio of right- to left-sided tumors

1.6:1

Reference

1. Yates D, Corrin B, Stidolph P, Browne K. Malignant mesothelioma in south east England: clinicopathological experience of 272 cases. Thorax 1997; 52:507-512.

Discussion