Histologic Changes

Another area of the decortication specimen had this appearance. Describe the features of these cells with respect to:

Cell shape

Nuclear/cytoplasmic ratio

Nucleolar size

Hyperchromaticity

These cells blended with the spindled cells.

Answer

In contrast to the picture above, in which the cells blended with spindled cells and showed no demarcation between tumor and stroma, this nest of tumor shows discrete epithelial differentiation that is distinct from the stroma at the top.

Clinical summary Image 3

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Answer

Another area of the decortication specimen had this appearance. Describe the neoplastic features of these cells with respect to:

Cell shape--polygonal, not spindled

Nuclear/cytoplasmic ratio--generally increased

Nucleolar size--enlarged (arrow)

Chromaticity--increased

These cells blended with the spindled cells.

Clinical summary Image 3

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