Histologic changes: Other parenchymal areas (A) show a diffuse, cellular interstitial pneumonia. A branching, edematous, fibrotic interlobular septum (ILS) crosses the field. A vein (V) is present in the septum. Alveolar walls are uniformly thickened and alveoli contain increased numbers of macrophages and some edema fluid.

A

At higher magnification (B), hypertrophied type II cells (arrows) line alveolar walls that are thickened by lymphoid cells and edema. Alveolar macrophages and proteinaceous exudate lie in the alveoli. Venules (V) are surrounded by lymphocytes, a common finding in immunologic reactions in the lung.

B

Case 10--Clinical summary Image 4

 

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